Demographic and clinical characteristics of all subjects, stratified by diabetes, enrolled in the Genetic and Inflammatory Markers of Sepsis (GenIMS) and Health, Ageing and Body Composition (Health ABC) study
| Variable | GenIMS study (n=1895) | Health ABC study (n=1645) | ||||
| All subjects | With diabetes (n=384) | Without diabetes (n=1511) | All subjects | With diabetes (n=299) | Without diabetes (n=1340) | |
| Demographics | ||||||
| Age, mean (SD, median) | 67.2 (16.8, 72) | 69.3 (14.5, 73) | 66.7 (17.3, 71) | 73.7 (2.8, 74) | 73.7 (2.8, 73) | 73.7 (2.8, 74) |
| Sex, female, n (%) | 910 (48.0) | 177 (46.1) | 733 (48.5) | 766 (46.7) | 132 (44.1) | 634 (47.3) |
| Race, white, n (%) | 1529 (80.7) | 307 (80) | 1222 (80.1) | 939 (57.2) | 127 (42.4) | 812 (60.6) |
| Health behaviours | ||||||
| Ever smoked, n (%) | 1262 (66.6) | 244 (63.5) | 1018 (67.4) | 997 (60.9) | 183 (61.6) | 814 (60.8) |
| Chronic health conditions | ||||||
| Respiratory disease, n (%) | 718 (37.9) | 148 (38.5) | 570 (37.7) | 320 (24.2) | 64 (27.4) | 256 (19.3) |
| Cardiovascular disease, n (%) | 488 (25.7) | 165 (42.9) | 323 (21.3)* | 438 (27.3) | 97 (35.9) | 341 (25.9)* |
| CKD, n (%) | 92 (4.8)† | 40 (10.4) | 52 (3.4)* | 403 (24.5) | 102 (34.1) | 301 (22.4)* |
| Cancer‡, n (%) | 94 (5.0) | 22 (5.7) | 72 (4.8) | – | – | – |
| HIV‡, n (%) | 37 (2.0) | 1 (0.3) | 36 (2.4)* | – | – | – |
↵* p<0.05 for comparison among subjects with and without diabetes.
↵† CKD diagnosis was available in 1571 (82.9%) subjects in GenIMS. In the remaining 324 subjects, CKD could not be ruled out based on history and because their plasma creatinine values were elevated on the first day of hospitalisation for pneumonia.
↵‡ Health ABC excluded subjects with active cancer and none reported HIV.
CKD, chronic kidney disease.