| SNP | Genotype | IL6 level (ln IL6 (pg/ml)) | ||
| N | Coefficient (SE) | p Value | ||
| II | 514 | |||
| IL6_-1479 | ID | 681 | −0.011 (0.046) | |
| (rs2069825) | DD | 229 | −0.080 (0.063) | 0.424† |
| IL6_-1363 | GG | 1185 | ||
| (rs2069827) | GT+TT | 234 | 0.000 (0.057) | 0.997† |
| GG | 483 | |||
| IL6_-174 | GC | 691 | 0.013 (0.047) | |
| (rs1800795) | CC | 255 | −0.056 (0.061) | 0.486† |
| CC | 234 | |||
| IL6_1754 | CG | 234 | 0.000 (0.048) | |
| (rs2069840) | GG | 72 | −0.030 (0.064) | 0.820‡ |
| GG | 169 | |||
| IL6_1889 | GT | 261 | 0.013 (0.044) | |
| (rs1554606) | TT | 110 | −0.057 (0.054) | 0.542‡ |
| AA | 431 | |||
| IL6_3331 | AG | 689 | 0.015 (0.049) | |
| (rs2069845) | GG | 293 | −0.020 (0.060) | 0.819† |
| AA | 685 | |||
| IL6_5909 | AG | 593 | 0.012 (0.044) | |
| (rs1818879) | GG | 137 | −0.025 (0.074) | 0.877† |
SNP, single nucleotide polymorphism.
*p Values were from genotype-based analysis (co-dominant genetic models) except for IL6_-1363 where p values were from a dominant genetic model because the minor allele frequency for this SNP was very low.
†Adjusted for body mass index, age, gender, pack years of smoking and smoking status.
‡Adjusted for body mass index, age, gender and pack years of smoking.