Table 5 Areas under the receiver operating characteristic curve (AUC) of the different models to predict 30-day mortality
AUC (95% CI)
PSI0.81 (0.75 to 0.87)
PSI+CRP*0.85 (0.80 to 0.91)
PSI+PCT0.83 (0.77 to 0.89)
PSI+CRP+PCT*0.85 (0.79 to 0.91)
PSI+CRP+IL6*0.86 (0.80 to 0.92)
PSI+CRP+IL8*0.87 (0.82 to 0.93)
CRB650.79 (0.72 to 0.87)
CRB65+CRP†0.85 (0.79 to 0.90)
CRB65+ PCT0.83 (0.76 to 0.89)
CRB65+CRP+PCT†0.86 (0.80 to 0.92)
CRB65+CRP+IL6†0.86 (0.80 to 0.92)
CRB65+CRP+IL8†0.88 (0.81 to 0.93)
CURB650.82 (0.76 to 0.89)
CURB65+CRP‡0.86 (0.81 to 0.92)
CURB65+PCT0.84 (0.77 to 0.90)
CURB65+CRP+PCT‡0.86 (0.79 to 0.92)
CURB65+CRP+IL6‡0.87 (0.82 to 0.92)
CURB-65+CRP+IL8‡0.88 (0.83 to 0.93)
PSI+CRB65+CRP*†0.87 (0.81 to 0.92)
PSI+CRB65+CRP+IL6*†0.88 (0.82 to 0.93)
PSI+CURB65+CRP*‡0.88 (0.83 to 0.93)
PSI+CURB65+CRP+IL6*‡0.88 (0.83 to 0.94)

  • *p<0.05 for comparison of AUCs with that of PSI.

  • †p<0.05 for comparison of AUCs with that of CRB65.

  • ‡p<0.05 for comparison of AUCs with that of CURB65.

  • CRB65, Confusion, Respiratory rate, Blood pressure, ≥65 years of age; CRP, C-reactive protein; CURB65, Confusion, Urea nitrogen, Respiratory rate, Blood pressure, ≥65 years of age; IL, interleukin; PCT, procalcitonin; PSI, Pneumonia Severity Index