| Control subjects(n = 15) | OSAS patients(n = 31) | |
| Age (years) | 48 (10) | 52 (13) |
| BMI (kg/m2) | 28.7 (4.7) | 30.5 (4.0) |
| Smokers (%) | 27 | 35 |
| Pack/years | 20 (7) | 20 (12) |
| AHI (/h) | 3.7 (3.3) | 43.8 (27.0)* |
| Mean Sao2 (%) | 94 (2) | 91 (6)‡ |
| Minimum Sao2 (%) | 85 (5) | 72 (15)‡ |
| CT90%Sao2 | 0.0 (0–0.05) | 6.3 (2.0–29.8)* |
| Desaturation index (/h) | 4.0 (3.0–7.5) | 41.2 (18.9–63.3)* |
| FVC (% predicted) | 99 (16) | 105 (17) |
| FEV1 (% predicted) | 108 (16) | 111 (15) |
| FEV1/FVC (%) | 88.2 (3.6) | 85.8 (7.2) |
| Daytime ambulatory BP (mm Hg) | ||
| Systolic | 122 (9) | 126 (10) |
| Diastolic | 78 (5) | 79 (6) |
| Night time ambulatory BP (mm Hg) | ||
| Systolic | 110 (10) | 117 (11) |
| Diastolic | 67 (6) | 70 (7) |
| Norepinephrine (μg/g) | ||
| Diurnal | 22.5 (19.6–30.1) | 33.2 (26.6–46.5) |
| Nocturnal | 11.3 (7.2–16.7) | 22.2 (13.9–29.4)† |
| Epinephrine (μg/g) | ||
| Diurnal | 6.9 (3.4–10.3) | 7.2 (4.0–11.8) |
| Nocturnal | 3.4 (2.2–4.9) | 6.3 (3.8–9.9)‡ |
| LVSF (%) | 40.1 (4.8) | 37.6 (3.1) |
| LVEF (%) | 70.1 (5.9) | 67.1 (3.7) |
*p<0.001, †p<0.01, ‡p<0.05 (Student t test or Mann-Whitney U test).
Values are mean (SD) or median (interquartile range) depending on the distribution.
AHI, apnoea-hypopnoea index; BMI, body mass index; BP, blood pressure; CT90%, percentage of total time study with Sao2 <90%; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LVEF, left ventricular ejection fraction; LVSF, left ventricular shortening fraction; OSAS, obstructive sleep apnoea syndrome; Sao2, oxygen saturation.