| Controls (n = 20) | Patients (n = 20) | |
| FEV1 (% predicted) | 105.1 (9.1) | 67.8 (25.8)** |
| Aortic PWV (m/s) | 8.8 (1.6) | 10.5 (3)* |
| Heart rate (bpm) | 65.4 (9.4) | 73.0 (11.9)* |
| SBP (mm Hg) | 142.8 (18.3) | 140.9 (14.3) |
| IL6 (pg/ml)† | 1.19 (3.7) | 4.41 (5.81)* |
| BMI (kg/m2) | 25.1 (4.6) | 25.8 (4.3) |
| Total FFMI (kg/m2) | 15.8 (2.4) | 15.8 (1.9) |
| Total hip BMD (g/cm2) | 0.90 (0.19) | 0.85 (0.13) |
| Total lumbar BMD (g/cm2) | 1.0 (0.19) | 0.93 (0.17) |
| 6MWD (m) | 352.5 (115.8) | 498.8 (86.4)** |
Values are mean (SD).
BMD, bone mineral density; BMI, body mass index; FEV1, forced expiratory volume in 1 s; FFMI, fat-free mass index; IL6, interleukin-6; 6MWD, 6-minute walk distance; PWV, pulse wave velocity; SBP, systolic blood pressure.
*p<0.05, **p<0.001 difference from controls.
†Geometric mean.