Table 4 Intra- and intergroup comparisons between the effectively treated group and the ineffectively treated group
Persistent OSA (ΔAHI ⩾50%) (n = 19)Improved OSA (ΔAHI <50%) (n = 17)p Value
Age at baseline (years)8.8 (7.5, 9.4)9.8 (8.2, 11.1)NS
Body mass index z score
    Baseline1.41 (0.67, 1.78)0.84 (−0.15, 1.82)NS
    Follow-up1.63 (0.76, 1.78)0.63 (−0.20, 1.82)NS
    *p ValueNSNS
    Change0.04 (−0.20, 0.22)0.10 (−0.13, 0.22)NS
Apnoea–hypopnoea index/h
    Baseline3.0 (2.3, 6.9)10.2 (2.6, 17.5)NS
    Follow-up6.0 (2.8, 7.8)0.8 (0.3, 3.4)<0.001
    *p ValueNS0.0003
    Change1.5 (−0.5, 4.2)−7.0 (−15.3, −2.3)<0.001
RV ejection fraction (%)
    Baseline51.5 (43.4, 60.3)47.2 (42.7, 58.5)NS
    Follow-up50.5 (36.7, 58.3)55.5 (45.1, 60.4)NS
    *p ValueNSNS
    Change−1.9 (−9.3, 3.5)1.7 (−1.9, 12.5)NS
RV myocardial performance index
    Baseline0.354 (0.321, 0.414)0.490 (0.408, 0.555)0.011
    Follow-up0.337 (0.288, 0.430)0.354 (0.288, 0.402)NS
    *p ValueNS0.025
    Change−0.03 (−0.16, 0.10)−0.11 (−0.25, 0.04)NS
Relative wall thickness
    Baseline0.338 (0.302, 0.376)0.372 (0.319, 0.464)NS
    Follow-up0.377 (0.333, 0.418)0.372 (0.311, 0.404)NS
    *p ValueNS0.039
    Change0.014 (−0.002, 0.074)−0.017 (−0.063, 0.001)0.006
Interventricular septal thickness index (cm/m)
    Baseline0.507 (0.490, 0.633)0.606 (0.500, 0.661)NS
    Follow-up0.540 (0.440, 0.648)0.528 (0.500, 0.577)NS
    *p ValueNS0.022
    Change−0.008 (−0.070, 0.120)−0.036 (−0.097, −0.008)NS
E/e′
    Baseline9.3 (8.7, 9.9)10.2 (8.8, 12.3)NS
    Follow-up9.4 (8.9, 11.2)9.1 (8.4, 9.9)NS
    *p ValueNS0.013
    Change0.3 (−0.8, 1.7)−1.4 (−3.2, −0.1)0.009
Abnormal LV geometry, N (%)
    Baseline7 (36.8)10 (58.8)NS
    Follow-up10 (52.6)8 (47.1)NS
    *p ValueNSNS
Acquired abnormal LV geometry (n (%))6 (31.6)2 (11.8)NS
Normalised LV geometry (n (%))3 (15.8)4 (23.5)NS
  • Data are shown as median (IQR) unless otherwise specified.

  • *p Values were obtained from Wilcoxon signed ranks tests (intragroup comparisons).

  • AHI, apnoea–hypopnoea index; E/e′, ratio of mitral early peak velocity/mitral annulus early peak velocity; LV, right ventricle; OSA, obstructive sleep apnoea; RV, right ventricle.