Total (n = 101) | Reference (n = 35) | Mild OSA (n = 39) | Moderate to severe OSA (n = 27) | p Value | |
Right ventricle (RV) | |||||
RV systolic volume index (ml/m)*† | 0.23 (0.09) | 0.18 (0.08) | 0.26 (0.10) | 0.25 (0.07) | <0.001 |
RV ejection fraction (%)*† | 53.4 (12.5) | 59.3 (11.0) | 51.4 (12.3) | 48.7 (11.9) | 0.001 |
RV myocardial performance index†‡ | 0.37 (0.12) | 0.32 (0.09) | 0.36 (0.09) | 0.46 (0.14) | <0.001 |
Left ventricle (LV) | |||||
LV systolic volume index (ml/m) | 22.6 (9.6) | 23.0 (9.8) | 23.0 (8.9) | 21.4 (10.5) | NS |
LV ejection fraction (%) | 66.2 (10.7) | 66.3 (10.1) | 64.4 (10.0) | 68.6 (12.1) | NS |
LV mass index (g/m2.7) | 32.6 (9.5) | 32.5 (7.8) | 30.3 (7.3) | 36.3 (12.9) | 0.04 |
Relative wall thickness‡ | 0.36 (0.07) | 0.36 (0.07) | 0.34 (0.06) | 0.39 (0.07) | 0.005 |
Interventricular septal thickness index (cm/m)‡ | 0.56 (0.09) | 0.56 (0.09) | 0.52 (0.09) | 0.60 (0.09) | 0.004 |
LV posterior wall thickness index (cm/m) | 0.52 (0.10) | 0.52 (0.10) | 0.50 (0.09) | 0.56 (0.11) | NS |
Abnormal LV geometry (n (%))§ | 43 (42.6) | 14 (40.0) | 9 (23.1) | 20 (74.1) | <0.001 |
LV myocardial performance index | 0.33 (0.11) | 0.32 (0.08) | 0.32 (0.12) | 0.35 (0.14) | NS |
E/A (mitral valve) | 2.2 (1.6) | 2.0 (0.6) | 2.6 (2.5) | 2.0 (0.4) | NS |
E/e′†‡ | 9.5 (1.8) | 9.1 (1.8) | 9.3 (1.4) | 10.4 (2.1) | 0.009 |
Data are shown as mean (SD) unless otherwise specified.
*p<0.05, normal group vs mild OSA group. †p<0.05, normal group vs moderate to severe OSA group. ‡p<0.05, mild OSA group vs moderate to severe OSA group. §p<0.016, normal group vs moderate to severe OSA group and mild OSA group vs moderate to severe OSA group.
E/A, ratio of early to late peak transtricuspid or transmitral flow; E/e′, ratio of mitral early peak velocity/mitral annulus early peak velocity; LV, left ventricular; OSA, obstructive sleep apnoea.