Table 2 Group comparisons of right and left ventricular structure and function
Total (n = 101)Reference (n = 35)Mild OSA (n = 39)Moderate to severe OSA (n = 27)p Value
Right ventricle (RV)
    RV systolic volume index (ml/m)*†0.23 (0.09)0.18 (0.08)0.26 (0.10)0.25 (0.07)<0.001
    RV ejection fraction (%)*†53.4 (12.5)59.3 (11.0)51.4 (12.3)48.7 (11.9)0.001
    RV myocardial performance index†‡0.37 (0.12)0.32 (0.09)0.36 (0.09)0.46 (0.14)<0.001
Left ventricle (LV)
    LV systolic volume index (ml/m)22.6 (9.6)23.0 (9.8)23.0 (8.9)21.4 (10.5)NS
    LV ejection fraction (%)66.2 (10.7)66.3 (10.1)64.4 (10.0)68.6 (12.1)NS
    LV mass index (g/m2.7)32.6 (9.5)32.5 (7.8)30.3 (7.3)36.3 (12.9)0.04
    Relative wall thickness‡0.36 (0.07)0.36 (0.07)0.34 (0.06)0.39 (0.07)0.005
    Interventricular septal thickness index (cm/m)‡0.56 (0.09)0.56 (0.09)0.52 (0.09)0.60 (0.09)0.004
    LV posterior wall thickness index (cm/m)0.52 (0.10)0.52 (0.10)0.50 (0.09)0.56 (0.11)NS
    Abnormal LV geometry (n (%))§43 (42.6)14 (40.0)9 (23.1)20 (74.1)<0.001
    LV myocardial performance index0.33 (0.11)0.32 (0.08)0.32 (0.12)0.35 (0.14)NS
    E/A (mitral valve)2.2 (1.6)2.0 (0.6)2.6 (2.5)2.0 (0.4)NS
    E/e′†‡9.5 (1.8)9.1 (1.8)9.3 (1.4)10.4 (2.1)0.009
  • Data are shown as mean (SD) unless otherwise specified.

  • *p<0.05, normal group vs mild OSA group. †p<0.05, normal group vs moderate to severe OSA group. ‡p<0.05, mild OSA group vs moderate to severe OSA group. §p<0.016, normal group vs moderate to severe OSA group and mild OSA group vs moderate to severe OSA group.

  • E/A, ratio of early to late peak transtricuspid or transmitral flow; E/e′, ratio of mitral early peak velocity/mitral annulus early peak velocity; LV, left ventricular; OSA, obstructive sleep apnoea.