| Enrolled subjects (n = 16) | Subjects with complete mechanical measurements (n = 6) | |
| Gender | 63% male | 83% male |
| Age (years) | 63 (8) | 67 (8) |
| Body mass index (kg/m2) | 27.8 (4.6) | 26.4 (3.8) |
| Cigarette smoking history (pack-years) | 44 (16) | 43 (18) |
| BDI focal score (0–12) | 8.3 (2.0) | 8.3 (1.9) |
| MRC dyspnoea scale (1–5) | 1.8 (0.7) | 1.5 (0.5) |
| CHAMPS (kcal/week consumed at moderate activities) | 2123 (2221) | 1736 (1974) |
| Symptom-limited peak exercise (% predicted maximum) | ||
| Work rate (W) | 121 (39), (72%) | 119 (30), (74%) |
| V̇o2 (l/min) | 1.84 (0.58), (79%) | 1.79 (0.58), (79%) |
| Pulmonary function (% predicted) | ||
| FEV1 post-bronchodilator (l) | 2.50 (0.58), (90%) | 2.44 (0.64), (86%) |
| FVC post-bronchodilator (l) | 4.25 (1.08), (108%) | 4.39 (1.18), (108%) |
| FEV1/FVC post-bronchodilator (%) | 59 (7), (84%) | 56 (8), (80%) |
| IC (l) | 3.01 (0.97), (103%) | 3.34 (1.13), (106%) |
| FRC (l) | 4.10 (0.91), (122%) | 4.45 (0.71), (126%) |
| TLC (l) | 7.11 (1.50), (113%) | 7.79 (1.32), (117%) |
| RV (l) | 2.83 (0.48), (129%) | 3.08 (0.32), (131%) |
| MIP (cm H2O) | 95 (32), (115%) | 87 (23), (95%) |
| MEP (cm H2O) | 149 (59), (83%) | 139 (44), (100%) |
| Tlco (ml/min/mm Hg) | 21.2 (5.9), (95%) | 22.4 (4.5), (106%) |
| sRaw (cm H2O.s) | 12.3 (4.0), (294%) | 13.3 (2.9), (303%) |
Values are shown as mean (SD), (% predicted normal values).
BDI, baseline dyspnoea index; MRC, Medical Research Council; CHAMPS, Community Healthy Activities Model Program for Seniors; FEV1, forced expiratory volume in 1 s; FRC, functional reserve capacity; FVC, forced vital capacity; IC, inspiratory capacity; MIP, maximal inspiratory mouth pressure; MEP, maximal expiratory mouth pressure; RV, residual volume; sRaw, specific airway resistance; TLC, total lung capacity; Tlco, carbon monoxide transfer factor; V̇o2, oxygen consumption.