Table 5 Relationships between individual inflammation-sensitive plasma proteins (ISPs) and hospital admissions for chronic obstructive pulmonary disease (COPD) over 25 years of follow-up

	Age-adjusted	Risk factor-adjusted*
Fibrinogen (per 0.8 g/l)	1.46 (1.3 to 1.6)	1.25 (1.1 to 1.4)
Haptoglobin (per 0.68 g/l)	1.69 (1.5 to 1.9)	1.34 (1.2 to 1.5)
Ceruloplasmin (per 0.067 g/l)	1.55 (1.4 to 1.7)	1.25 (1.1 to 1.4)
α₁-Antitrypsin (per 0.27 g/l)	1.50 (1.3 to 1.7)	1.16 (1.0 to 1.3)
Orosomucoid (per 0.20 g/l)	1.49 (1.3 to 1.7)	1.26 (1.1 to 1.4)

Expressed as hazards ratios (95% confidence interval) per 1 standard deviation.
*Adjusted for age, current and former smoking, body mass index, forced expiratory volume in 1 s (% of predicted values) and chronic bronchitis.