Model | Covariables | Regression coefficients (95% CI) | p Value | Model r2 | |
Healthy (n = 26) | I | (1) FFM | 6.0 (0.9 to 11.1) | 0.024 | 0.59 |
(2) Sex (F − M) | −120.2 (−214.1 to −26.3) | 0.014 | |||
COPD (n = 30) | II | (1) FFM | 2.4 (−1.7 to 6.5) | 0.240 | 0.30 |
(2) Sex (F − M) | −62.1 (−120.8 to −3.3) | 0.039 | |||
III | (1) MRCDS | −76.2 (−106.3 to −46.1) | <0.001 | 0.49 | |
IV | (1) FFM | 0.6 (−2.8 to 4.1) | 0.708 | 0.55 | |
(2) Sex (F − M) | −36.9 (−87.1 to 31.2) | 0.142 | |||
(3) MRCDS | −62.2 (−96.1 to −28.3) | 0.001 |
FFM, fat-free mass (in kg); RFCSA, rectus femoris cross-sectional area (in mm2); MRCDS, Medical Research Council dyspnoea score.
Results of regression analyses performed to investigate the relationship of FFM and sex with RFCSA in mm2. All regression models included a constant value. Regression coefficients describe the change in the RFCSA (as the dependent variable) per unit change of each covariable.