Table 2

Characteristics of baseline quantitative CT assessments of subjects

Mean (SD)Range
Total lung volume(ml)5086.2 (1350.3)2608.1–9861.1
Mean lung density (g/ml)0.2 (0.0)0.1–0.2
Lung overinflation
    %overinflation58.4 (16.4)15.9–83.7
    Cluster analysis1.5 (0.2)1.2–2.1
        Upper zone predominantn = 102
        Diffuse distributionn = 7
        Lower zone predominantn = 34
Emphysema
    %LAA(−950 HU)2.9 (2.6)0.2–13.3
    Cluster analysis3.1 (0.4)2.1–4.4
        Upper zone predominantn = 35
        Diffuse distributionn = 10
        Lower zone predominantn = 98
Airway dimensions
    Lumen area, Ai (mm2)6.8 (2.3)2.1–15.1
    WA %76.8 (3.5)67.5–84.9
    √Aaw at Pi10 (mm)4.4 (0.2)3.9–5.1
  • Aaw, airway wall area; Ai, lumen area; LAA, low attenuation lung area; Pi, lumen perimeter; WA %, wall area expressed as the percentage of the total airway area.

  • %overinflation, (volume of overinflated lung/volume of total lung) × 100%; %LAA (−950 HU), (volume of lung areas with x ray attenuation lower than −950 HU/volume of total lung) × 100%; WA%, (airway wall area/(airway wall area + lumen area))×100%; √Aaw at Pi10 (mm), √Aaw for a standardised airway with an internal perimeter (ie, Pi) of 10 mm.