Abstract S37 Table
VariableBaselinePost step-downp Value
BDP equivalent ICS dose (μg/day)635.96 (35.7)357.02 (18.9)<0.001
Mannitol (PD10 mg/ml)†99.99 (1.15)137.19 (1.15)0.04
Exhaled nitric oxide†26.79 (1.10)27.93 (1.09)0.43
Spirometry‡
    FEV1 % predicted86.16 (1.51)84.46 (1.46)0.04
    FVC % predicted91.56 (1.38)91.52 (1.44)0.97
    PEF % predicted90.20 (1.70)90.02 (1.56)0.87
AQLQ
    Average score per question5.45 (0.10)5.83 (0.09)<0.001
    Symptoms26.11 (0.55)28.23 (0.51)<0.001
    Activity limitations25.91 (0.63)28.38 (0.55)<0.001
    Emotional function27.18 (0.54)28.96 (0.51)<0.001
    Environmental stimuli27.00 (0.56)29.09 (0.49)<0.001
    Total score81.60 (1.50)87.40 (1.38)<0.001
  • *Data presented as arithmetic mean (SEM) unless otherwise indicated. Baseline values are shown after washout before each randomised treatment period. †Shown as geometric mean (geometric SEM). ‡Expressed as a percentage of that predicted by age, sex, and height. AQLQ, asthma quality of life questionnaire; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ICS, inhaled corticosteroids; PC10, provocative concentration of mannitol causing a 10% decrease in FEV1; PEF, peak expiratory flow rate.