Morbidity attached to upper airways disease | Reduction in inflammation may improve quality of life |
Similar mucosal surfaces and inflammatory response | Potential marker of lower airway disease |
Potential site for future research to assess drug responses |
Treatment may reduce lower respiratory inflammation |
Paranasal sinuses and nose may act as reservoir for respiratory pathogens | Pseudomonas eradication regimens may require sinonasal elimination |
Treatment of sinonasal disease may reduce frequency of lower respiratory infection |
Treatment for lung transplant patients may reduce recolonisation of transplanted lung |