Table 5 Results of three logistic regression analyses to predict treatment failure, early and late
MeasurementsTreatment failureEarly failureLate failure
OR (95% CI)p ValueOR (95% CI)p ValueOR (95% CI)p Value
Day 1
    IL6 (pg/ml)1.9 (1.1–3.4)0.02——2.3 (1.1–4.7)0.02
    IL8 (pg/ml)2.2 (1.3–3.9)0.003——2.8 (1.4–5.7)0.003
    CRP (mg/dl)2.6 (1.5–4.6)0.0012.6 (1.2–5.5)0.012.6 (1.3–5.3)0.009
    PCT (ng/ml)—2.7 (1.3–5.8)0.01——
    Fine IV-V vs I-III1.7 (1.1–2.9)0.042.6 (1.2–5.9)0.01——
Day 1 and 3
    IL6 day 3 (pg/ml)2.6 (1.3–5,3)0.005——4.2 (1.8–9.6)0.001
    CRP day 3 (mg/dl)3.4 (1.7–6.7)0.001——4.8 (2.1–11.2)0.0001
    Fine IV-V vs I-III1.9 (1.1–3.6)0.04————
    PCT day 3 (ng/ml)——————

  • CRP, C reactive protein; IL, interleukin; PCT, procalcitonin.