Table 2 Pulmonary function and methacholine bronchial challenge in adolescents with and without self-reported current wheezing
Current wheezing (n = 95)Without current wheezing (n = 97)
Baseline FVC (%predicted)114.8 (12.1)116.0 (12.7)
Baseline FEV1 (%predicted)116.7 (12.3)120.3 (14.5)
Baseline FEV1/FVC (%predicted)89.2 (5.3)90.3 (5.5)
PC20 <8 mg/ml (%)**71.652.6
Positive skin test (%)44.242.3

  • **p<0.01.

  • FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; PC20, provocative concentration of methacholine required to decrease FEV1 by 20% from saline.