Table 5 Comparative outcomes of four regimens in the treatment of lung diseases caused by MAC, M malmoense and M xenopi
MACM malmoenseM xenopiTotal
REREHREClariRECiproREREHREClariRECiproREREHREClariRECipro
No of patients373883875254868122201717594
Deviated from protocol16%21%35%43%29%22%24%43%14%25%59%47%32%
Deaths (all causes)32%39%48%30%33%35%42%56%55%85%29%47%42%
Deaths (due to mycobacteria)0%8%2%3%2%6%5%2%0%15%0%6%4%
Failures of treatment and relapses41%16%13%23%12%9%5%5%18%5%24%6%14%
Completed treatment as allocated, alive and cured at 5 years27%34%24%23%38%44%38%20%23%10%18%12%28%
  • Clari, clarithromycin; Cipro, ciprofloxacin; H, isoniazid; E, ethambutol; MAC, Mycobacterium avium intracellulare; R, rifampicin.

  • Percentages do not always add up to 100% because some patients who died had earlier been failures of treatment or relapses.