| Baseline | Air | Oxygen | NIV | |
| CF QoL (0 = worst, 100 = best) | ||||
| Physical functioning | 69 (20) | 68 (22) | 64 (21) | 67 (19) |
| Chest symptoms | 65 (13) | 64 (20) | 68 (20) | 71 (17)† |
| Treatment issues | 58 (15) | 67 (20) | 63 (35) | 65 (21) |
| Emotional responses | 83 (11) | 85 (11) | 83 (13) | 79 (18) |
| CSQ (0 = worst, 100 = best) | 42 (16) | 56 (22) | 50 (11) | 58 (13) |
| ESS (0 = best, 24 = worst) | 9 (5) | 7 (5) | 7 (6) | 7 (5) |
| Global PSQI (0 = best, 21 = worst) | 7 (3) | 7 (3) | 6 (2) | 6 (3) |
| MRC (0 = best, 4 = worst) | 2.4 (0.9) | 2.6 (1.2) | 2.5 (0.8) | 2.6 (1.0) |
| TDI (−9 = worst, +9 = best) | 5.8 (2.7)* | −1.9 (2.5) | −0.4 (1.5) | 1.0 (1.8)† |
Values are mean (SD).
*Baseline Dyspnoea Index score (0 = worst, 12 = best).
†p<0.02, mean difference from baseline (NIV vs air).
CF, cystic fibrosis; CF QoL, Cystic Fibrosis Quality of Life questionnaire; CSQ, Cystic Fibrosis Subjective Sleep Disturbance Questionnaire; ESS, Epworth Sleepiness Scale; Global PSQI, global score of the Pittsburgh Sleep Quality Index; MRC, Medical Research Council Dyspnoea Scale; NIV, non-invasive positive pressure ventilation; TDI, Transition Dyspnoea Index.