| Screened (n = 60) | Randomised (n = 8) | Declined (n = 5) | Randomised vs declined p value | |
| Age (y) | 31 (8) | 37 (8) | 24 (5) | 0.004 |
| Sex (M:F) | 36:24 | 6:2 | 2:3 | |
| Homozygous ΔF508 (%) | 56 | 60 | 100 | |
| BMI (kg/m2) | 20.8 (3.2) | 21.1 (2.6) | 18.0 (2.9) | 0.10 |
| FEV1 (% pred) | 42 (13) | 35 (8) | 27 (9) | 0.13 |
| RV/TLC (%) | 52 (11) | 59 (8) | 64 (7) | 0.26 |
| pH | 7.41 (0.03) | 7.39 (0.02) | 7.42 (0.03) | 0.05 |
| Paco2 (mm Hg) | 42 (5) | 52 (4) | 47 (4) | 0.05 |
| Pao2 (mm Hg) | 75 (11) | 63 (5) | 60 (5) | 0.37 |
| HCO3 (mmol/l) | 26 (3) | 30 (3) | 30 (3) | 0.72 |
| Sao2 (%) | 96 (3) | 93 (3) | 92 (2) | 0.34 |
Values are mean (SD).
BMI, body mass index; FEV1, forced expiratory volume in 1 s; Paco2, arterial carbon dioxide pressure; Pao2, arterial oxygen pressure; RV, residual volume; Sao2, arterial oxygen saturation; TLC, total lung capacity.