| Characteristic | RAGE measured (n = 676) | Not measured (n = 226) | p Value |
| Age (years) (mean (SD)) | 51 (17) | 52 (18) | 0.43 |
| Female gender | 394 (58) | 143 (63) | 0.19 |
| Race/ethnicity | 0.61 | ||
| White | 497 (69) | 164 (73) | |
| Black | 118 (17) | 37 (16) | |
| Hispanic | 39 (6) | 12 (5) | |
| Asian/Pacific Islander | 17 (3) | 9 (4) | |
| Native American | 3 (0.4) | 3 (1.3) | |
| Other | 2 (0.3) | 1 (0.4) | |
| APACHE III score (mean (SD)) | 82.0 (27.5) | 86.5 (31.5) | 0.05 |
| Sepsis as primary ALI risk factor | 173 (26) | 63 (28) | 0.50 |
| Trauma as primary ALI risk factor | 63 (9) | 33 (15) | 0.03 |
| Pao2:Fio2 ratio (mean (SD)) | 128 (58) | 135 (58) | 0.11 |
| Diabetes | 97 (14) | 29 (13) | 0.55 |
| End stage renal disease | 18 (3) | 2 (1) | 0.12 |
| Lower tidal volume arm | 352 (52) | 121 (54) | 0.70 |
| WBC (/103) (mean (SD)) | 14.9 (1.0) | 14.5 (1.1) | 0.55 |
| Lowest MAP (mean (SD)) | 62.1 (14) | 61.5 (14) | 0.57 |
Data reported as n (%) unless otherwise specified.
ALI, acute lung injury; APACHE, Acute Physiology and Chronic Health Evaluation; MAP, mean arterial pressure; Fio2, fractional inspired oxygen; Pao2, arterial oxygen tension; RAGE, receptor for advanced glycation end products; WBC, white blood cell count.