Table E1 The list of medications taken by each patient during the study period

Patient	Medications	Patient	Medications
1	Salbutamol 100 mcg inh bd	8	Salbutamol 100 mcg inh qds
	Tiotropium 18 mcg inh od		Iprtropium 20 mcg inh bd
	Beclometasone dipropionate 200 mcg inh bd		Theophylline modified release 175 mg po bd
	Aspirin 75 mg po od		Seretide (250 mcg/50 mcg) inh bd
			Gliclazide 80 mg po od
2	Salmeterol 50 mcg inh bd
	Salbutamol 100 mcg inh prn	9	Salbutamol 100 mcg inh prn
	Budesonide 200 mcg inh bd
	Ipratropium 40 mcg inh bd
	Theophylline modified release 250 mg po bd
3	Salmeterol 100 mcg inh bd	10	Salmeterol 50 mcg inh bd
	Salbutamol 100 mcg inh bd		Salbutamol 100 mcg inh prn
	Ipratropium 40 mcg inh bd		Fluticasone propionate 200 mcg inh bd
	Fluticasone propionate 100 mcg inh bd
	Ranitidine 300 mg po od
4	Seretide (250 mcg/50 mcg) inh bd	11	Salbutamol 100 mcg inh qds
	Salbutamol 100 mcg inh prn		Ipratropium 20 mcg inh bd
			Fluticasone propionate 250 mcg inh bd
5	Salmeterol 50 mcg inh bd	12	Salmeterol 50 mcg inh bd
	Salbutamol 100 mcg inh prn		Salbutamol 100 mcg inh prn
	Ipratropium 20 mcg inh bd		Fluticasone propionate 250 mcg inh bd
	Beclometasone dipropionate 20 mcg inh bd
	Paracetamol 1 g po QDS
6	Salmeterol 50 mcg inh bd	13	Combivent inh (100 mcg/20 mcg) inh qds
	Salbutamol 100 mcg inh prn		Beclometasone dipropionate 200 mcg inh bd
	Ipratropium 20 mcg inh qds
7	Ipratropium 20 mcg inh bd
	Fluticasone propionate 250 mcg inh bd	14	Formoterol fumarate 4.5 mcg inh bd
	Lansoprazole 15 mg po od		Tiotropium 18 mcg inh od
	Warfarin 3 mg po od (variable dose)
	Furosemide 20 mg po od

Medications taken during the study period. Medications did not change for 8 weeks prior to the study or during the study period.