Table 3 Baseline levels of leukotrienes LTE₄ and LTB₄ and 9α,11β-PGF₂ in urine, blood ex vivo, sputum supernatant and saliva

Sample	Mediator	AIA (n = 11)	ATA (n = 10)	p Value
Urine (ng/mmol creatinine)	9α,11β-PGF₂	47 (40–71)	42 (36–43)	0.171
Urine (ng/mmol creatinine)	LTE₄	90 (66–120)	41 (35–52)	<0.001
Blood ex vivo (ng/ml)	LTB₄	81 (34–109)	45 (33–59)	0.218
Blood ex vivo (ng/ml)	LTE₄	55 (36–115)	19 (18–32)	0.003
Sputum supernatant (ng/ml)	LTB₄	2.6 (1.7–3.6)	3.1 (2.3–3.7)	0.460
Sputum supernatant (ng/ml)	LTE₄	8.2 (7.4–12.3)	5.5 (4.1–6.8)	0.010
Saliva (pg/ml)	LTB₄	434 (283–893)	358 (334–572)	0.460
Saliva (pg/ml)	LTE₄	144 (113–157)	69 (51–109)	0.007

Data are presented as median (interquartile range).
AIA, aspirin-intolerant asthma; ATA, aspirin-tolerant asthma.