Regression coefficient(95% CI) | p Value | |
Height at age 11 years | 3.266 (2.124 to 4.409) | <0.001 |
PD20 <7.8 μg histamine at age 11 years | −0.246 (−0.439 to −0.053) | 0.013 |
Log V′maxFRC/length at 1 month | 1.127 (0.496 to 1.758) | 0.001 |
% change in V′maxFRC between 1 and 12 months | 0.012 (0.001 to 0.024) | 0.039 |
% change in weight between 1 and 12 months | 0.003 (0.000 to 0.006) | 0.068 |
FEF25–75, mid expiratory flow; PD20, dose of histamine provoking a fall in forced expiratory volume in 1 s of ⩾20%; V′maxFRC, maximal flow at functional residual capacity;
Data from 121 individuals are included. Neither birth weight, exclusive breast feeding to 6 months of age nor atopy at 11 years were related to FEF25–75 and did not remain in the model. There was a significant (p = 0.031) and positive interaction term between percentage change in weight and height at 11 years.