| Outcome | Variable | OR (95% CI) | p Value |
| Severe disease (CURBage score) | Age (per 1 year increase) | 1.09 (1.05 to 1.14) | <0.001 |
| Male sex | 3.26 (1.36 to 7.82) | 0.008 | |
| Rhinovirus infection (with concomitant pneumococcal infection) | 9.95 (1.31 to 75.34) | 0.03 | |
| Rhinovirus infection (without concomitant pneumococcal infection) | 0.18 (0.02 to 1.81) | 0.15 | |
| Severe disease (PSI risk class) | Age (per 1 year increase) | 1.17 (1.11 to 1.23) | <0.001 |
| Male sex | 2.50 (1.04 to 5.98) | 0.04 | |
| Current smoker | 3.28 (1.03 to 10.45) | 0.05 | |
| Rhinovirus infection (with concomitant pneumococcal infection) | 11.52 (1.09 to 121.89) | 0.04 | |
| Rhinovirus infection (without concomitant pneumococcal infection) | 0.18 (0.04 to 0.87) | 0.03 |
PSI, Pneumonia Severity Index.