Table 4 Association analysis of TLR7 and TLR8 SNPs

	Asthma		Rhinitis		Atopic dermatitis		Positive RAST
	Additive	Recessive	Additive	Recessive	Additive	Recessive	Additive	Recessive
Sample A
SNP1 (TLR7)							0.066
A^OT
SNP9 (TLR8)	0.054	0.047	0.074	0.019		0.058
G^OT	0.018 (G)	0.0071 (G)		0.016 (G)		0.046 (G)		0.025 (G)

Sample B
SNP1 (TLR7)	0.012 (B)	0.056	0.013	0.0071			0.027	0.0090
A^OT		0.012 (B)	0.0054 (B)	0.0054 (B)	0.020 (B)	0.020 (B)	0.011 (B)	0.011 (B)
SNP9 (TLR8)	0.00069	0.00053			0.066	0.052	0.083	0.061
G^OT	0.0035 (B)	0.0035 (B)
	0.046 (G)	0.059 (G)

Sample A+B
SNP1 (TLR7)	0.069	0.018	0.025	0.0053		0.074	0.0047	0.0044
A^OT	0.0092 (B)	0.0092 (B)	0.0039 (B)	0.0039 (B)	0.024 (B)	0.024 (B)	0.0052 (B)	0.0052 (B)
SNP9 (TLR8)	0.00025	0.00023	0.033	0.012	0.021	0.00066	0.063	0.014
G^OT	0.035 (B)	0.035 (B)		0.037 (G)	0.069 (G)	0.016 (G)		0.0077 (G)
	0.0020 (G)	0.0010 (G)

Only p values <0.1 are included in the table. p Values ⩽0.05 are indicated in bold type.
B and G, boys and girls, respectively (values with no letter represent the total); OT, overtransmitted allele; RAST, radioallergosorbent test; SNP, single nucleotide polymorphism; TLR, Toll-like receptor.