Table 3 Changes in exercise tolerance after 3 months of treatment
BaselineAfter 3 monthsChange within groupBetween group difference in change (95% CI)
6MWD (m)
    N+R318 (131)340 (119)222 (−19 to 23)
    R304 (112)325 (108)22
ESWT (s)
    N+R283 (232–503)475 (295–1010)166103 (−69 to 276)
    R327 (187–831)449 (213–1042)0
Borg max
    N+R5.7 (2.3)4.4 (2.0)1.3−0.8 (−1.8 to 0.1)
    R5.3 (2.0)5.0 (2.2)0.3
Vo2max (ml/min/kg)
    N+R9.1 (2.4)9.8 (2.9)0.70.3 (−0.9 to 1.4)
    R9.1 (2.7)9.5 (3.0)0.5
Daily step count (steps/day)
    N+R1893 (591–3773)2799 (891–6135)3911269 (242–2296)*
    R1680 (699–3538)2093 (914–3155)93
  • Mean (SD) for 6MWD, Borg max and PWR. Median (interquartile range (IQR)) and median changes for ESWT and daily step count.

  • *Significant difference in change between groups.

  • ESWT, endurance shuttle walk test, Borg max, maximum Borg score at ESWT; 6MWD, 6-minute walking distance; N+R, non-invasive positive pressure ventilation (NIPPV) + rehabilitation group; R, rehabilitation group, Vo2max, maximal oxygen uptake at peak cycle exercise performance.