Table 1 Clinical and functional characteristics of subjects
Normal(n = 11)COPD ex-smokers(n = 5)COPD smokers(n = 10)Asthma(n = 11)
Male/female5/65/010/09/2
Age (years)37 (21–42)69 (61–73)63 (53–71)27 (18–41)
Atopy+
PC20 (FEV1) (mg/ml)>16N/AN/A2.72 (0.52–6.96)
FEV1 (% predicted)110 (92–135)30 (21–52)46 (23–68)102 (89–116)
FEV1/FVC (%)86 (72–92)41 (24–46)56 (31–63)82 (71–100)
Smoking history (pack years)Non-smokers98 (45–129)43 (24–102)Non-smokers
Stop years (years)N/A3 (1–12)0N/A
  • FEV1 forced expiratory volume in 1 s; FVC, forced vital capacity; PC20, concentration of histamine that causes a 20% fall in FEV1; N/A, not applicable.

  • Data presented as median (range) or absolute values where appropriate.