Table 1 Association between LTA use and pattern of organ involvement
LTA typeLungCardiacNerveSkin
p ValueOR (95% CI)p ValueOR (95% CI)p ValueOR (95% CI)p ValueOR (95% CI)
Univariate analysis
    Pranlukast0.140.2 (0.02 to 1.8)*0.0060.15 (0.03 to 0.6)*0.092.9 (0.8 to 10.6)*0.710.8 (0.2 to 2.6)*
    Zafirlukast0.151.9 (0.5 to 7.1)*0.323.1 (0.3 to 29.3)*0.710.001 (0 to 1×1017)*0.282.1 (0.5 to 8.1)*
    Montelukast0.351.00.0031.00.231.00.411.0
Multivariate analysis
    Pranlukast0.430.5 (0.1 to 3.2)*0.010.1 (0.03 to 0.7)*0.055.6 (0.97 to 32)*0.10.9 (0.2 to 3.5)
    Zafirlukast0.098.3 (0.8 to 59)*0.62.0 (0.2 to 24)*0.80.6 (0.01 to 246)*0.95.6 (0.8 to 40)
    Montelukast0.111.00.031.00.151.00.21.0
  • We performed univariate and multivariate logistic regression examining predictors of the pattern of organ expression (dependent variable), the latter controlling for antineutrophil cytoplasmic antibody status and patient group.

  • *Compared with montelukast. LTA, leukotriene antagonist.