Tertiles of adiponectin | BMI category | Premenopausal women | |
No with current asthma/total | OR (95% CI) | ||
Tertile 1 | Underweight and normal weight | 5/88 | 1 |
Overweight | 10/130 | 1.82 (0.58 to 5.72) | |
Obese | 47/277 | 5.77 (1.96 to 17.01) | |
p Value for Wald χ2 | 0.001 | ||
Tertile 2 | Underweight and normal weight | 15/186 | 1 |
Overweight | 14/145 | 1.21 (0.56 to 2.62) | |
Obese | 22/156 | 1.93 (0.87 to 4.24) | |
p Value for Wald χ2 | 0.24 | ||
Tertile 3 | Underweight and normal weight | 8/259 | 1 |
Overweight | 8/98 | 2.30 (0.80 to 6.63) | |
Obese | 3/52 | 1.11 (0.24 to 5.14) | |
p Value for Wald χ2 | 0.26 |
All models were adjusted for age, race, smoking status, ln(physical activity), history of diabetes and ln(insulin resistance).
The interactions between BMI categories and serum adiponectin on current asthma status were not significant (p = 0.45). Similar results were obtained when BMI and ln(adiponectin) were used as continuous variables (p = 0.75).
Adiponectin tertile cut-off points used in the above analysis were derived from premenopausal women (1.2–9.0, 9.0–15.0 and 15.0–94.8 mg/l).
Similar results were obtained when the underweight and normal weight categories were analysed separately with the latter serving as the referent category.
BMI categories are defined as follows: underweight <18.5 kg/m2; normal weight 18.5–24.9 kg/m2; overweight 25.0–29.9 kg/m2; obese ⩾30 kg/m2.
BMI, body mass index; CI, confidence interval; OR, odds ratio.