| Group | Baseline cough threshold (mol/l), mean (SD) | Difference in mean after intervention amiloride-placebo | 95% CI | p Value | ||
| Lower | Upper | |||||
| Healthy (n = 18) | C2 | 0.559 (0.9) | −0.27 | −0.82 | 0.29 | 0.329 |
| C5 | 1.372 (1.2) | −0.30 | −0.64 | 0.04 | 0.079 | |
| Asthma (n = 11) | C2 | 0.402 (0.9) | −0.29 | −1.37 | 0.78 | 0.556 |
| C5 | 0.897 (1.4) | 0.07 | −0.41 | 0.55 | 0.750 | |
| Idiopathic (n = 11) | C2 | 0.024 (0.3) | −0.03 | −0.09 | 0.04 | 0.385 |
| C5 | 0.075 (0.1)* | −0.12 | −0.38 | 0.14 | 0.313 | |
| All cough (n = 22) | C2 | 0.213 (0.7) | −0.01 | −0.47 | 0.44 | 0.955 |
| C5 | 0.486 (1.0) | 0.00 | −0.22 | 0.21 | 0.984 | |
| All subjects (n = 40) | C2 | 0.369 (0.8) | −0.12 | −0.46 | 0.22 | 0.477 |
| C5 | 0.885 (1.2) | −0.13 | −0.32 | 0.06 | 0.169 | |
*p = 0.01.