Clinical characteristics of 54 patients with ALI/ARDS and 28 patients with hydrostatic pulmonary oedema from whom plasma and pulmonary oedema fluid were obtained, and 12 patients from whom lung tissue was obtained for immunohistochemistry
| Characteristic | Patients from whom plasma and oedema fluid samples were obtained | Patients from whom lung tissue was obtained for immunohistochemistry | ||
|---|---|---|---|---|
| ALI/ARDS(N = 54) | Hydrostatic(N = 28) | ALI/ARDS(N = 6) | Non-ALI/ARDS(N = 6) | |
| ALI/ARDS, acute lung injury/acute respiratory distress syndrome. | ||||
| Data presented as n (%) or mean (SD). | ||||
| †p = 0.009 vs ALI/ARDS; ‡p<0.001 vs ALI/ARDS; §p = 0.006 vs ALI/ARDS; ¶p = 0.001 vs ALI/ARDS. | ||||
| *Lung injury score.20 | ||||
| **SAPSII, Simplified Acute Physiology Score II.21 | ||||
| Male, n (%) | 30 (56%) | 15 (54%) | 4 (73%) | 1 (16%) |
| Caucasian, n (%) | 36 (67%) | 16 (58%) | 6 (100%) | 6 (100%) |
| Mean (SD) age (years) | 42 (16) | 54 (20)† | 41 (16) | 53 (20) |
| Current smokers, n (%) | 10 (19%) | 8 (29%) | 1 (16%) | 1 (16%) |
| Sepsis, n (%) | 23 (43%) | 0 (0%)‡ | ||
| Mean (SD) lung injury score* | 3.0 (0.7) | 2.5 (0.7) | 3.6 (0.5) | 1.5 (1.2) |
| Mean (SD) tidal volume (ml/kg) | 10.1 (2.9) | 10.5 (2.1) | ||
| Mean (SD) SAPSII** | 48 (19) | 39 (15) | 62 (15) | 49 (18) |
| Mean (SD) ventilator-free days | 9 (11) | 17 (11)§ | ||
| Hospital mortality, n (%) | 29 (54%) | 5 (19%)¶ | 6 (100%) | 6 (100%) |