Age, sex and risk factors for acute renal failure (ARF)
| No | Age (y) | Sex | Aminoglycoside | Prior/concurrent* | Ceftazidime | Nebulised antibiotic† | Other nephrotoxic drug | Other risk factor |
|---|---|---|---|---|---|---|---|---|
| c, concurrent; e, ever; IV, intravenous; CFRD, cystic fibrosis-related diabetes; MRSA, methicillin-resistant Staphylococcusaureus; | ||||||||
| *Timing of aminoglycoside in relation to ARF: concurrent, at the time ARF diagnosed; prior, within the week prior to ARF. | ||||||||
| †Patients receiving nebulised tobramycin had intravenous solution in nebulised form. | ||||||||
| 1 | 0.4 | M | Gentamicin | Prior | Yes | Colistin (e) | Diarrhoea and vomiting | |
| 2 | 21.1 | F | Gentamicin | Concurrent | Yes | Colistin (e) | Diclofenac (c) | |
| 3 | 6.9 | M | Gentamicin then tobramycin | Prior/concurrent | Yes | None | ||
| 4 | 5.0 | M | Gentamicin | Concurrent | Yes | None | Fever | |
| 5 | 5.7 | M | Gentamicin | Concurrent | No | Gentamicin (c) | Neonatal renal cortical necrosis | |
| 6 | 11.9 | F | Tobramycin | Concurrent | No | Colistin (c) | Ibuprofen (c) | Fever |
| 7 | 4.4 | M | Gentamicin | Prior | Yes | Colistin (e) | ||
| 8 | 18.6 | F | None | Colistin (c) | ‘Flu-like illness following oral rifampicin and ciprofloxacin. CFRD | |||
| 9 | 12.3 | F | Gentamicin | Prior | Yes | Tobramycin (c) | Ciclosporin (e) | |
| 10 | 17.0 | F | Tobramycin | Concurrent | No | Colistin (c) | Toxic shock. Clostridium difficile toxin in stool | |
| 11 | 31.8 | F | Gentamicin | Prior | Yes | Gentamicin (e) | CFRD and diabetic nephropathy | |
| 12 | 9.6 | M | Gentamicin | Concurrent | Yes | Colistin (c) | Ciclosporin (c) | CFRD |
| 13 | 3.6 | M | Gentamicin | Concurrent | Yes | Colistin (c) | Diarrhoea and vomiting | |
| 14 | 7.4 | M | Gentamicin | Prior | Yes | Colistin (c) | Previous pseudo Barter’s syndrome | |
| 15 | 9.8 | M | Tobramycin | Concurrent | No | Gentamicin (e) | Indomethacin (c) | |
| 16 | 15.0 | M | Tobramycin | Concurrent | No | Tobramycin (c) | CFRD, ventilated, MRSA septicaemia | |
| 17 | 15.9 | F | Tobramycin | Concurrent | No | Colistin (c) | Colistin (IV) | CFRD |
| 18 | 9.8 | M | Gentamicin | Concurrent | No | None | Naproxen (e) and diclofenac (e) | Constipation, osmotic laxatives |
| 19 | 3.6 | M | Gentamicin | Concurrent | Yes | Colistin (c) | Gastro-oesophageal reflux, vomiting | |
| 20 | 12.1 | F | None | None | Naproxen (c) | RhF +ve arthritis | ||
| 21 | 17.3 | F | None | Colistin (e) | CFRD | |||
| 22 | 8.0 | F | Gentamicin | Prior | Yes | Colistin (c) | ||
| 23 | 8.0 | F | Gentamicin | Concurrent | Yes | Colistin (c) | ||
| 24 | 9.0 | F | Gentamicin | Prior | Yes | Colistin (c) | ||