Relative (% baseline) bronchodilator responses
| Healthy(n = 78) | CF(n = 39) | nCLD(n = 49) | Asthma(n = 56) | Wheeze(n = 66) | |
|---|---|---|---|---|---|
| Data shown as median relative change with bronchodilator (10th, 90th percentile). Numbers in bold indicate a significant difference compared with the healthy group (p<0.05, multiple linear regression for each group adjusted for covariates). | |||||
| CF, cystic fibrosis; nCLD, neonatal chronic lung disease; Rrs6, Rrs8, Rrs10, respiratory resistance at 6, 8 and 10 Hz; Xrs6, Xrs8, and Xrs10, respiratory reactance at 6, 8 and 10 Hz. | |||||
| ΔRrs6 (%) | −21.3 (−35.0, −3.1) | −16.8 (−32.1, −0.6) | −23.3 (−33.0, −9.2) | −14.9 (−37.0, 8.8) | −16.0 (−37.9, 8.4) |
| ΔXrs6 (%) | 27.4 (−7.5, 50.0) | 23.5 (−5.1, 46.7) | 31.9 (4.0, 49.8) | 27.0 (−13.8, 57.3) | 28.4 (−6.5, 59.9) |
| ΔRrs8 (%) | −18.7 (−35.0, −4.4) | −14.8 (−26.7, 4.1) | −19.2 (−33.0, −5.2) | −16.0 (−33.1, 9.7) | −16.3 (−33.1, 8.9) |
| ΔXrs8 (%) | 30.9 (−1.6, 62.6) | 30.0 (−6.5, 56.1) | 38.8 (16.4, 63.2) | 30.3 (−7.8, 58.9) | 32.2 (−7.8, 60.9) |
| ΔRrs10 (%) | −18.8 (−32.3, −3.7) | −15.0 (−26.8, 4.3) | −18.2 (−27.5, −4.9) | −14.7 (−33.4, 4.5) | −15.3 (−33.4, 3.0) |
| ΔXrs10 (%) | 29.3 (−0.2, 53.9) | 29.4 (0.3, 53.6) | 35.5 (14.3, 56.9) | 32.7 (−7.0, 57.5) | 33.9 (0.0, 58.4) |