Table 2 Diagnoses and survival in 102 HIV-infected patients admitted to the ICU on 113 occasions
Diagnosisn (%)New diagnosis of HIV infection(n)Receiving HAART(n)ICU survival N (%)Hospital survival N (%)
LRTI54 (48)241340 (74)28 (52)
    PCP*†2618218 (69)15 (58)
    Bacterial pneumonia‡§173711 (65)9 (53)
    Tuberculosis¶7307 (100)6 (86)
    Asthma/COPD3033 (100)3 (100)
    CMV pneumonitis1011 (100)1 (100)
Neurological problems16 (14)5514 (87)12 (75)
    CMV encephalitis**1101 (100)0 (0)
    Cerebral toxoplasmosis3113 (100)3 (100)
    Cryptococcal meningitis3113 (100)3 (100)
    Intracranial bleed††3012 (67)1 (33)
    Uncontrolled epilepsy2011 (50)1 (50)
    Tuberculous meningitis1101 (100)1 (100)
    Bacterial meningitis1001 (100)1 (100)
    HIV encephalopathy2112 (100)2 (100)
Sepsis‡‡10 (9)056 (60)6 (60)
Post-cardiac arrest7 (6)053 (43)1 (14)
Postoperative7 (6)137 (100)7 (100)
Variceal haemorrhage5 (4)043 (60)2 (40)
HAART-related§§3 (3)033 (100)2 (67)
Miscellaneous¶¶11 (10)1410 (91)9 (82)
  • LRTI, lower respiratory tract infection; PCP, Pneumocystis jirovecii pneumonia; COPD, chronic obstructive pulmonary disease; CMV, cytomegalovirus; IRIS, immune reconstitution inflammatory syndrome; HAART, highly active antiretroviral therapy.

  • *Six patients were also treated for other opportunistic infections during their admission to the ICU (3 had CMV pneumonitis, 2 had pulmonary tuberculosis and 1 had CMV encephalitis).

  • †One patient was re-admitted to the ICU with PCP as a manifestation of IRIS.

  • ‡One patient also had cerebral toxoplasmosis.

  • §One patient was undergoing chemotherapy for non-Hodgkin’s lymphoma.

  • ¶Two patients also had PCP and two others had CMV encephalitis.

  • **One patient also had tuberculous meningitis.

  • ††Two patients suffered intracranial haemorrhages as a complication of end-stage chronic viral liver disease.

  • ‡‡Three patients presented with sepsis without localising features as a complication of chemotherapy for HIV-related malignancies.

  • §§Two patients had lactic acidosis and one had IRIS.

  • ¶¶Six patients had drug overdose, one had trauma and four had miscellaneous causes.