Pearson correlation coefficients (r) of baseline variables with airway hyperresponsiveness (dose response ratio, DRR) for the asthmatic group as a whole and for the treatment subgroup before and after treatment
| Baseline asthma group(n = 40) | Baseline treatment subgroup(n = 18) | Post-treatment treatment subgroup(n = 18) | ||||
|---|---|---|---|---|---|---|
| r | p Value | r | p Value | r | p Value | |
| FEV1, forced expiratory volume in 1 s; FeNO, fraction of nitric oxide in exhaled breath; FVC, forced vital capacity; LCI, lung clearance index; Scond, ventilation heterogeneity in conducting airways; Sacin, ventilation heterogeneity in acinar lung zone | ||||||
| Airway inflammation (FENO) | 0.62 | <0.001 | 0.51 | 0.03 | 0.61 | 0.008 |
| Ventilation heterogeneity (Scond) | 0.63 | <0.001 | 0.64 | 0.004 | 0.82 | <0.001 |
| Ventilation heterogeneity (Sacin) | 0.07 | 0.67 | 0.04 | 0.86 | −0.02 | 0.93 |
| Ventilation heterogeneity (LCI) | 0.38 | 0.02 | 0.31 | 0.21 | 0.47 | 0.05 |
| FEV1 % predicted | −0.44 | 0.005 | −0.40 | 0.10 | −0.37 | 0.13 |
| FEV1/FVC ratio | −0.47 | 0.002 | −0.34 | 0.17 | −0.21 | 0.41 |