Table 1 Demographic and lung function characteristics of patients with COPD (n = 15) and age-matched healthy subjects (n = 10)
COPDControls
Age (years)66 (7)61 (5)
BMI (kg/m2)25.9 (2.7)28.8 (2.6)
FEV1 (l) [% pred]0.94 (0.44) [35.7 (16.4)]2.86 (0.8) [94.7 (5.4)]*
FVC (l) [% pred]2.47 (0.82) [71.3 (20.0)]3.76 (0.9) [101.3 (11)]*
FEV1/FVC (%)36 (11)77 (4)*
Tlco (% pred)40.2 (16.8)81.2 (5.9)*
TLC (l) [% pred]7.92 (1.24) [126 (9)]6.16 (0.21) [95 (3)]*
FRC (l) [% pred]5.83 (0.76) [172 (14)]3.22 (0.11) [96 (4)]*
RV (l) [% pred]4.52 (0.82) [209 (30)]1.93 (0.09) [88 (7)]*
IC (l) [% pred]2.09 (0.60) [72 (10)]2.96 (0.18) [92 (5)]*
Pao2 (mmHg)65.1 (9.5)_
Paco2 (mmHg)39.8 (2.6)_
pH7.44 (0.20)_
Sao2 (%)92.8 (2.2)_

  • Values are mean (SD).

  • BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; Tlco, carbon monoxide transfer factor; TLC, total lung capacity; FRC, functional residual capacity; RV, residual volume; IC, inspiratory capacity; Pao2, Paco2, arterial oxygen and carbon dioxide tensions; Sao2, oxygen saturation.

  • *p<0.05 vs COPD (unpaired t test).