Table 1 Clinical characteristics of patients with eosinophilic asthma, non-eosinophilic asthma and normal controls
Normal controlsEosinophilic asthmaNon-eosinophilic asthmap Value(ANOVA)p Value (eosinophilic vs non-eosinophilic)
Number (men)10 (5)12 (8)11 (3)
Age (years)41 (22–61)42 (27–69)47 (19–68)0.65
FEV1 (% predicted)105 (3.9)90.3 (6.2)88 (4.9)0.050.96
FEV1/FVC82 (1.8)73.9 (2.9)69 (5.6)0.0250.58
β2 agonist reversibilty (%)1.1 (0.9)9.5 (2.5)12.7 (3.4)0.0010.67
Methacholine PC20 (mg/ml)>160.67 (0.2)0.83 (0.2)<0.0010.15
Atopic (%)2 (20)8 (66)2 (18)
  • Data given as mean (SE) except age which is given as mean (range) and methacholine PC20 which is given as geometric mean (log SE).

  • FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; β2 agonist reversibility, percentage increase in FEV1 following inhalation of 200 μg salbutamol; methacholine PC20, concentration of inhaled methacholine which causes a 20% fall in FEV1.