Lung function status at various intervals in relation to time of starting treatment
| Interval from study entry | Lung function compared with baseline | Treatment started at entry or within 3 months of entry, n (%) | Treatment started later or not at all, n (%) | χ2 test for trend,p value |
|---|---|---|---|---|
| Only patients still alive at the relevant year were included in this analysis. Patients who had been started on treatment before study entry were excluded from this analysis. | ||||
| *Unknown as less than the relevant period of follow-up available. | ||||
| 1 year | n = 71 | n with data = 116 | ||
| 173 dead | Better | 26 (37) | 24 (21) | χ2 = 2.2, |
| 411 alive | Same | 16 (22) | 42 (36) | p = 0.14 |
| 4 unknown* | Worse | 29 (41) | 50 (43) | |
| 2 years | n = 49 | n = 92 | ||
| 254 dead | Better | 15 (31) | 17 (19) | χ2 = 0.2, |
| 324 alive | Same | 6 (13) | 28 (30) | p = 0.67 |
| 10 unknown* | Worse | 28 (57) | 47 (51) | |
| 3 years | n = 35 | n = 66 | ||
| 311 dead | Better | 17 (49) | 7 (11) | χ2 = 14.1, |
| 261 alive | Same | 4 (11) | 14 (21) | p<0.001 |
| 16 unknown* | Worse | 14 (40) | 45 (68) | |
| 4 years | n = 25 | n = 52 | ||
| 355 dead | Better | 10 (40) | 4 (8) | χ2 = 9.1, |
| 195 alive | Same | 4 (16) | 12 (23) | p = 0.003 |
| 38 unknown* | Worse | 11 (44) | 36 (69) | |