Subject characteristics and clinical measures at study commencement for CF and control participants divided into two age groups: children (5–10 years) and adolescents (11–18 years)
| CF | Control | p value | |||
|---|---|---|---|---|---|
| N | Mean (SD) | N | Mean (SD) | ||
| Values are mean (SD) unless otherwise stated. | |||||
| BMD, bone mineral density; FEV1, forced expiratory volume in 1 second. | |||||
| Children | |||||
| F/M | 40 | 21/19 | 32 | 18/14 | 0.81 |
| Age (years) | 40 | 8.5 (1.8) | 32 | 8.5 (1.5) | 0.89 |
| Weight Z-score | 40 | 0.02 (0.97) | 32 | 0.28 (1.09) | 0.28 |
| Height Z-score | 40 | −0.22 (0.95) | 32 | 0.21 (1.06) | 0.10 |
| Total body BMD Z-score | 40 | 0.23 (0.74) | 32 | 0.26 (0.70) | 0.87 |
| Lumbar spine BMD Z-score | 40 | −0.28 (0.95) | 32 | −0.31 (0.99) | 0.88 |
| FEV1 (%) median (range) | 39 | 84 (46–116) | |||
| FVC (%) median (range) | 39 | 93 (53–122) | |||
| Adolescents | |||||
| N (F/M) | 45 | 18/27 | 68 | 36/32 | 0.19 |
| Age (years) | 45 | 14.1 (2.2) | 68 | 13.9 (1.9) | 0.47 |
| Weight Z-score | 45 | −0.75 (0.91) | 68 | 0.26 (0.82) | <0.001 |
| Height Z-score | 45 | −0.87 (0.84) | 68 | 0.59 (0.97) | <0.001 |
| Total body BMD Z-score | 45 | −1.29 (1.48) | 68 | 0.37 (0.93) | <0.001 |
| Lumbar spine BMD Z-score | 45 | −0.53 (1.22) | 68 | −0.18 (1.24) | <0.001 |
| FEV1 (%) median (range) | 45 | 86 (23–124) | |||
| FVC (%) median (range) | 45 | 90 (36–123) | |||