Effect of inhaled dust extract on serum antibody production in mice
| Treatment | IgE(×105 U/ml) | IgG1(×105 U/ml) | IgG2a(OD405) |
|---|---|---|---|
| PBS, phosphate buffered saline; LPS, lipopolysaccharide. | |||
| Serum levels of OVA specific IgE, IgG1, IgG2a were measured by ELISA and expressed as arbitrary units; n ⩾8 per group. The results are presented as median with the 25–75th percentile in parentheses. Dust extract treated mice were compared with PBS treated mice by the two tailed Mann-Whitney test. | |||
| PBS | 2.7 (1.7–5.6) | 11.1 (8.1–19.6) | 0.15 (0.13–0.27) |
| LPS | 2.2 (1.3–5.6) | 13.3 (8.4–26.7) | 0.14 (0.13–0.3) |
| Dust extract | 1.3 (0.9–2.0), p = 0.017 | 5.5 (2.0–8.1), p = 0.001 | 0.17 (0.13–0.2) |
| Non-sensitised | 0 | 0 | 0.09 |