Maximal and submaximal exercise responses in patients by HRCT findings 6 months after SARS diagnosis
| Adjusted mean (SE)* | Adjusted mean difference(95% CI) | p value | ||
|---|---|---|---|---|
| Normal HRCT scan(n = 20) | Abnormal HRCT scan(n = 14) | |||
| V˙o2, oxygen consumption; V˙e, minute ventilation; HR, heart rate; RER, respiratory exchange ratio; RR, respiratory rate; V˙e/V˙o2, V˙e/V˙co2, ventilatory equivalent for oxygen and carbon dioxide; Peto2, Petco2, end tidal oxygen and carbon dioxide partial pressures; VAT, ventilatory anaerobic threshold; OUES, oxygen uptake efficiency slope. | ||||
| *Values are adjusted for the z score of weight for age. | ||||
| Resting V˙o2 (ml/min) | 229.3 (13.3) | 201.6 (15.9) | −27.8 (−70.3 to 14.8) | 0.193 |
| Respiratory quotient | 0.87 (0.02) | 0.86 (0.02) | −0.01 (−0.06 to 0.04) | 0.752 |
| Resting HR (beats/min) | 88.3 (3.3) | 86.7 (3.9) | −1.6 (−12.1 to 8.9) | 0.753 |
| Resting RR (breaths/min) | 18.8 (1.0) | 19.7 (1.2) | 0.9 (−2.4 to 4.2) | 0.572 |
| Resting V˙e (l/min) | 9.1 (0.4) | 8.8 (0.5) | −0.3 (−1.6 to 1.0) | 0.620 |
| Peak V˙o2 (ml/min) | 1668.9 (131.9) | 1294.0 (158.1) | −374.9 (−797.8 to 48.1) | 0.080 |
| Peak V˙o2 (ml/kg/min) | 30.5 (1.7) | 23.0 (2.0) | −7.5 (−12.9 to −2.1) | 0.008 |
| Peak RER | 1.2 (0.02) | 1.2 (0.02) | 0.04 (−0.02 to 0.10) | 0.153 |
| Peak HR (beats/min) | 193.4 (2.0) | 192.7 (2.4) | −0.7 (−7.1 to 5.7) | 0.823 |
| Peak O2 pulse (ml/beat) | 8.7 (0.7) | 6.7 (0.9) | −2.1 (−4.4 to 0.3) | 0.080 |
| Peak RR (breaths/min) | 50.5 (2.4) | 51.6 (2.9) | 1.1 (−6.6 to 8.8) | 0.689 |
| Peak V˙e (l/min) | 71.8 (3.6) | 65.2 (4.3) | −6.6 (−18.0 to 4.9) | 0.250 |
| Peak V˙e/V˙o2 | 45.8 (2.4) | 53.5 (2.8) | 7.7 (0.1 to 15.3) | 0.049 |
| Peak V˙e/V˙co2 | 40.0 (2.0) | 44.4 (2.4) | 4.4 (−2.0 to 10.7) | 0.172 |
| Peto2 (mm Hg) | 93.0 (3.6) | 91.0 (4.3) | −2.1 (−13.5 to 9.3) | 0.714 |
| Petco2 (mm Hg) | 32.5 (1.7) | 29.4 (2.0) | −3.0 (−8.3 to 2.2) | 0.248 |
| VAT (ml/min) | 979.4 (78.7) | 793.3 (94.4) | −186.1 (−438.5 to 66.3) | 0.143 |
| OUES | 712.7 (62.6) | 562.9 (71.9) | −149.8 (−344.9 to 45.3) | 0.128 |
| Exercise time (s) | 602.2 (48.0) | 569.2 (61.9) | −33.0 (−194.0 to 127.9) | 0.679 |