Demographic data, risk factors, medical co-morbidity, performance status, source of referral, and mode of presentation of all lung cancer patients diagnosed in the year 2000 in Teesside and Varese
| Teesside(n = 268) | Varese(n = 243) | p value | |
|---|---|---|---|
| *Occupations and industries known or suspected to be associated with lung cancer.13 †Not available: 11 patients. ‡Not available: 43 patients. §Not available: 82 patients. ¶Not available: 83 patients. **Not available: 17 patients. ††Not available: 119 patients. ‡‡Not available: 4 patients. §§Not available: 5 patients. ¶¶Not available: 128 patients. ***Not available: 142 patients. †††Not available: 15 patients. ‡‡‡Not available: 20 patients. §§§Pack years in smokers and former smokers. ¶¶¶Mann-Whitney U test. | |||
| Mean (SD) age (years) | 69 (10) | 67 (10) | 0.032 |
| M/F (ratio) | 153/115 (1.33) | 200/43 (4.65) | <0.001 |
| Risk factors | |||
| Smoker (%) | 142/257 (55%)† | 111/243 (46%) | <0.001 |
| Former smoker (%) | 105/257 (41%)† | 99/243 (41%) | |
| Never smoker (%) | 10/257 (4%)† | 33/243 (13%) | |
| Median pack years§§§ | 45.5‡ | 45.0§ | 0.659¶¶¶ |
| Occupational risk (%)* | 93/185 (50%)¶ | 69/226 (31%)** | <0.001 |
| Family history of lung cancer | 20/149 (13%)†† | 37/239 (15%)‡‡ | 0.578 |
| No of patients with co-morbidity (%) | 193/263 (73%)§§ | 156/243 (64%) | 0.026 |
| Performance status 0–1 | 38% | 62% | <0.001 |
| Performance status 2–4 | 62% | 38% | |
| FEV1 (% predicted) | 63% (22)¶¶ | 78% (23)*** | <0.001 |
| Source of referral to lung cancer specialist | |||
| GP, urgent/emergency | 64% | 61% | 0.502 |
| GP, routine | 20% | 14% | 0.108 |
| Other consultant | 16% | 23% | 0.076 |
| Chest radiography screening | 0% | 2% | 0.018 |
| Mode of presentation | |||
| Asymptomatic diagnosis by chest radiography | 17/253 (7%)††† | 47/223 (21%)‡‡‡ | |
| Diagnosis by symptoms | 236/253 (93%)††† | 176/223 (79%)‡‡‡ | |