Median (5th/95th centile) outcome measures of the three groups at 1 and 6 months
| Group 1:6 months autotitration | Group 2:1 week autotitration | Group 3:Algorithm | p value between groups | |
|---|---|---|---|---|
| ESS, Epworth Sleepiness Score; MWT, maintenance of wakefulness test; PCS, physical component summary; MCS, mental component summary; EV, energy and vitality dimension; SAQLI, Sleep Apnea Quality of Life Index. | ||||
| ESS | ||||
| Pre CPAP | 16.0 (10.6/23.0) | 17.0 (10.4/22.6) | 16.5 (10.5/22.3) | 0.7 |
| 1 month | 7.0 (1.0/12.0) | 7.0 (0/15.4) | 6 .0 (1.0/19.8) | 0.9 |
| 6 months | 6.0 (0.45/13.8) | 5.0 (0/15.5) | 5.0 (0.5/12.5) | 0.8 |
| MWT (min) | ||||
| Pre CPAP | 19.4 (1.4/40.0) | 19.5 (2.9/40) | 15.7 (2.1/40) | 0.8 |
| 1 month | 40.0 (5.1/40.0) | 40.0 (5.5/40.0) | 31.3 (3.1/40) | 0.1 |
| 6 months | 40.0 (11.6/40.0) | 40.0 (14.5/40) | 40.0 (2.2/40) | 0.2 |
| Mean BP (mm Hg) | ||||
| Pre CPAP | 95.8 (77.0/122.0) | 95.2 (77.3/118.3) | 96.2 (75.0/120.6) | 0.9 |
| 1 month | 93.3 (73.0/115.0) | 93.3 (78.0/108.0) | 96.4 (84.0/115.0) | 0.4 |
| 6 months | 99.6 (77.3/119.0) | 96.7 (82.7/119.0) | 96.4 (73.3/114.3) | 0.5 |
| SF-36 PCS | ||||
| Pre CPAP | 62.5 (17.2/93.2) | 65.7 (25.2/90.0) | 62.6 (25.9/92.5) | 0.6 |
| 1 month | 79.7 (35.1/95.4) | 81.7 (33.1/94.5) | 81.3 (30.5/98.7) | 0.8 |
| 6 months | 78.8 (20.0/96.2) | 85.2 (26.6/95.3) | 83.3 (40.9/98.3) | 0.5 |
| SF-36 MCS | ||||
| Pre CPAP | 57.2 (19.8/87.5) | 56.8 (26.0/89.4) | 56.6 (16.6/88.7) | 0.9 |
| 1 month | 77.7 (32.5/93.6) | 82.3 (39.7/94.0) | 81.8 (24.4/97.6) | 0.9 |
| 6 months | 79.3 (30.5/94.1) | 81.5 (27.8/95.0) | 82.7 (35.4/95.4) | 0.9 |
| SF-36 EV | ||||
| Pre CPAP | 25.0 (6.0/74.0) | 30.0 (0/78.0) | 27.5 (3.8/72.5) | 0.9 |
| 1 month | 65.0 (30.0/87.5) | 60.0 (24.0/90.0) | 60.0 (23.3/100.0) | 0.9 |
| 6 months | 67.5 (19.0/82.8) | 67.5 (35.0/94.9) | 60.0 (42.0/94.0) | 1.0 |
| Change in SAQLI | ||||
| 1 month | 1.4 (−3.2/4.3) | 1.5 (−4.0/4.5) | 0.8 (−5.4/3.7) | 0.2 |
| 6 months | 1.6 (−4.8/4.3) | 1.5 (−5.6/4.7) | 1.4 (−5.2/3.4) | 0.7 |