Table 2

Association between TNF2 allele and asthma

Reference	TNF2 vs TNF1		TNF2/2 vs TNF1/1		TNF2/2 vs TNF2/1		TNF2/1 vs TNF1/1		TNFα-308+		LTα NcoI+
Reference	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	1	2	1	2
+, A significant (p<0.05) association with the + allele increased and the – allele decreased in asthmatics; 1 = G, 2 = A; NS, not significant difference.
Moffatt⁶	1.63	1.06 to 2.52	3.20	1.23 to 8.28	1.65	0.63 to 4.37	1.94	1.17 to 3.22	–	+	+	–
Chagni⁹	1.54	1.07 to 2.23							–	+
Li Kam¹⁰	1.34	1.01 to 1.78	2.21	1.07 to 4.56	1.97	0.93 to 4.16	1.12	0.78 to 1.61	–	+
Louis¹¹	1.05	0.61 to 1.81					1.24	0.67 to 2.30	NS	NS
Winchester¹²	2.93	1.53 to 5.47	4.02	0.85 to 19.00	1.36	0.28 to 6.56	2.96	1.30 to 6.75	–	+
Zhu¹³	0.41	0.13 to 1.28					2.06	0.51 to 8.24	NS	NS
Witte¹⁵	1.35	0.92 to 1.98	0.86	0.24 to 3.10	0.55	0.15 to 2.04	1.58	1.04 to 2.37	–	+	NS	NS
Buckova¹⁶	1.40	0.90 to 2.19	3.41	0.35 to 33.32	2.48	0.25 to 24.80	1.38	0.83 to 2.28	NS	NS	NS	NS
Gao¹⁷	1.46	0.99 to 2.16	2.21	0.98 to 5.01	1.87	0.82 to 4.20	1.19	0.66 to 2.12	–	+	NS	NS
Di Somma¹⁸	2.44	1.11 to 5.34							NS	NS
Beghe¹⁹	1.27	0.58 to 2.74							NS	NS
Sandford²¹	2.60	1.00 to 3.69					2.07	1.04 to 4.12	–	+
Shin²²	0.39	0.25 to 0.59	0.27	0.04 to 1.95	0.74	0.10 to 5.50			+	–	NS	NS
Wang²³	1.32	0.74 to 2.32					2.16	1.19 to 3.91	–	+	NS	NS
Bilolikar²⁴	1.60	1.07 to 2.40	1.60	0.50 to 5.07	0.77	0.24 to 2.51	2.08	1.15 to 3.75	–	+	–	+