Results of multivariate analysis of risk factors for default, retreatment, and death from TB among bacteriologically confirmed pulmonary TB patients, Orizaba Veracruz, 1995–2003
| Characteristic | Default | Retreatment | Death from TB | |||
|---|---|---|---|---|---|---|
| OR* (95% CI) | p value | HR† (95% CI) | p value | HR† (95% CI) | p value | |
| OR, odds ratio; HR, hazards ratio; MDR, multidrug resistant; TB, tuberculosis; –, variable not included in the final model. | ||||||
| *Logistic regression analysis. | ||||||
| †Cox proportional hazard model. | ||||||
| Men | 3.30 (1.46 to 7.43) | 0.004 | 3.15 (1.38 to 7.22) | 0.007 | 2.23 (1.25 to 3.99) | 0.007 |
| Age (years) | – | – | – | – | 1.04 (1.02 to 1.05) | <0.001 |
| No formal education | 3.85 (1.85 to 8.33) | <0.001 | – | – | – | – |
| No social security | 4.54 (1.64 to 12.5) | 0.003 | – | – | – | – |
| Body mass index | – | – | – | – | 2.28 (1.38 to 3.79) | 0.001 |
| Weight loss | – | – | – | – | 2.40 (1.02 to 5.63) | 0.04 |
| Diabetes | – | – | 1.83 (0.94 to 3.54) | 0.073 | – | – |
| HIV infection | – | – | – | – | 24.30 (9.0 to 65.6) | <0.001 |
| MDR TB | – | – | 4.96 (1.99 to 12.36) | 0.001 | 2.84 (1.25 to 6.40) | 0.01 |
| Other resistance | – | – | 1.33 (0.57 to 3.10) | 0.52 | 0.7 (0.34 to 1.43) | 0.3 |
| Cavities in chest radiograph | 3.70 (1.81 to 7.58) | <0.001 | – | – | – | – |
| Time interval between diagnosis and treatment (months) | 1.02 (1.01 to 1.04) | <0.001 | – | – | – | – |
| Treatment default | – | – | – | – | 5.21 (3.06 to 8.87) | <0.001 |