COPD patients | Control smokers (S) | Control non-smokers (NS) | |
---|---|---|---|
FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; TLC, total lung capacity; FRC, functional residual capacity; Tlco, carbon monoxide transfer factor, MRC, Medical Research Council dyspnoea scale; 6MWT, 6 minute walk test; V̇o2peak, peak oxygen consumption. | |||
Results are expressed as mean (SD); geometric means are presented for non-normally distributed variables. | |||
All variables shown in table 2 were significantly different for COPD patients v controls. There was no difference between the two control groups. | |||
FEV1 (%) | 37 (11) | 91 (15) | 92 (17) |
FEV1/FVC (%) | 42 (11) | 73 (6) | 75 (6) |
TLC (%) | 130 (23) | 101 (18) | 102 (20) |
FRC (%) | 174 (38) | 99 (25) | 105 (29) |
Tlco (%) | 52 (21) | 89 (22) | 96 (20) |
MRC | 2.2 (0.9) | 0.5 (0.7) | 0.2 (0.4) |
6MWT (m) | 375 (99) | 546 (75) | 558 (102) |
Watts | 64 (29) | 119 (37) | 131 (41) |
V̇o2peak (ml/kg/min) | 10 (4) | 20 (5) | 21 (7) |