Inflammatory markers in patients with normal and raised CRP levels and in healthy controls
| COPD | Controls | ||
|---|---|---|---|
| Normal CRP | Raised CRP | ||
| Values presented as median (range). | |||
| TNF-α, tumour necrosis factor α; sTNF-R55/75, soluble TNF-receptor 55/75; IL-6, interleukin 6. | |||
| *p<0.05 v healthy controls. | |||
| †p<0.03 v normal CRP levels. | |||
| TNFα (pg/ml) | 1.25 (0.60–3.42) | 1.31 (0.43–3.19) | 1.23 (0.74–2.70) |
| sTNF-R55 (ng/ml) | 0.87 (0.54–2.51) | 1.00 (0.59–2.20)† | 0.88 (0.59–1.46) |
| sTNF-R75 (ng/ml) | 1.42 (0.81–3.39) | 1.54 (0.84–3.33)* | 1.14 (0.68–1.82) |
| IL-6 (pg/ml) | 2.60 (1.00–11.45)* | 6.45 (0.90–12.85)*† | 1.76 (0.81–6.00) |