COPD(n = 28) | Never smokers(n = 20) | Smokers(n = 14) | Former smokers(n = 14) | |
---|---|---|---|---|
FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; ICS, inhaled corticosteroids. | ||||
Data are presented as median (IQR). | ||||
*p<0.01 v never smokers; †p<0.001 v smokers; ‡p<0.05 v former smokers; §p<0.001 v never smokers; ¶p<0.001 v never smokers, smokers and former smokers. | ||||
Sex ratio (M/F) | 24/4 | 4/16 | 7/7 | 7/7 |
Age (years) | 64.0 (52–72)*†‡ | 52.5 (42–56) | 51.0 (49–53) | 52.5 (46–63) |
Smoking history (pack years) | 42.0 (26–55)‡§ | 0.0 (0–0) | 35.0 (16–43) | 30.0 (9–42) |
FEV1 (l) | 2.0 (1.7–2.3)¶ | 3.0 (2.7–3.4) | 3.0 (2.5–3.3) | 3.4 (2.7–3.7) |
FEV1 (% predicted) | 70.0 (63–78)¶ | 105.5 (97–118) | 96.0 (91–101) | 108.0 (100–113) |
FEV1/FVC (%) | 56.0 (49–65)¶ | 80.5 (77–83) | 78.0 (73–82) | 78.5 (75–80) |
Bronchodilators (Y/N) | 20/8 | 0/20 | 0/14 | 0/14 |
ICS (Y/N) | 17/11 | 0/20 | 0/14 | 0/14 |