Variables | Anti-GM-CSF antibodies in blood | Anti-GM-CSF antibodies in BAL fluid | ||
---|---|---|---|---|
Correlation coefficient | p value | Correlation coefficient | p value | |
Anti-GM-CSF antibodies, anti-granulocyte-macrophage colony stimulating factor antibodies; BAL, bronchoalveolar lavage; LDH, lactate dehydrogenase; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; TLC, total lung capacity; Tlco, carbon monoxide transfer factor; HRCT, high resolution computed tomography. | ||||
*Pao2 and AaPo2 were measured in the sitting position at room air. | ||||
AaPo2 = Pao2 – Pao2; Pao2 = (barometric pressure − 47) × Fio2 − Paco2/0.8. | ||||
Serum LDH (IU/l) | 0.04 | 0.906 | 0.58 | 0.039 |
Pao2 (kPa)* | −0.27 | 0.376 | −0.69 | 0.009 |
AaPo2 (kPa)* | 0.38 | 0.201 | 0.77 | 0.002 |
FEV1 (% pred) | −0.15 | 0.629 | −0.11 | 0.738 |
FVC (% pred) | −0.21 | 0.498 | −0.22 | 0.471 |
TLC (% pred) | −0.02 | 0.949 | −0.44 | 0.133 |
Tlco (% pred) | −0.06 | 0.856 | −0.62 | 0.024 |
Chest radiographs | ||||
Opacity score | 0.32 | 0.283 | 0.65 | 0.016 |
Extent score | 0.17 | 0.578 | 0.42 | 0.158 |
Severity score | 0.12 | 0.678 | 0.50 | 0.080 |
Chest HRCT | ||||
Opacity score | 0.08 | 0.805 | 0.35 | 0.242 |
Extent score | 0.01 | 0.978 | 0.74 | 0.004 |
Severity score | 0.07 | 0.812 | 0.48 | 0.100 |
Reticulation score | −0.04 | 0.898 | 0.58 | 0.038 |