Clinical characteristics of patients with idiopathic pulmonary alveolar proteinosis
| Case | Age at diagnosis (years) | Sex(M/F) | Serum LDH(IU/l)* | Pao2(kPa)† | AaPo2(kPa)† | Length of follow up(years) | Clinical course | Status at last follow up |
|---|---|---|---|---|---|---|---|---|
| *LDH, lactate dehydrogenase (reference value 95–213 IU/l). | ||||||||
| †Pao2 and AaPo2 were measured in the sitting position at room air. | ||||||||
| AaPo2 = Pao2 – Pao2; Pao2 = (barometric pressure − 47) × Fio2 − Paco2/0.8. | ||||||||
| TLL, therapeutic lung lavage; SI, spontaneous improvement; DOE, dyspnoea on exertion. | ||||||||
| 1 | 53 | M | 239 | 10.8 | 3.4 | 4 | Stable | Symptom free |
| 2 | 40 | F | 389 | 6.4 | 7.8 | 8 | TLL at diagnosis | O2 treatment, repeated TLL |
| 3 | 40 | M | 269 | 11.3 | 1.6 | 5 | Stable | Symptom free |
| 4 | 31 | M | 292 | 9.7 | 3.3 | 4 | TLL at diagnosis | Symptom free |
| 5 | 16 | M | 280 | 8.8 | 5.2 | 3 | SI | Symptom free |
| 6 | 18 | F | 289 | 10.8 | 3.4 | 6 | SI | Symptom free |
| 7 | 54 | F | 242 | 10.7 | 2.8 | 6 | Stable | Mild DOE |
| 8 | 36 | F | 175 | 10.9 | 3.1 | 3 | Stable | Symptom free |
| 9 | 59 | F | 265 | 8.1 | 6.0 | 4 | TLL 2 years after diagnosis | Symptom free |
| 10 | 33 | M | 191 | 10.1 | 3.5 | 6 | SI | Symptom free |
| 11 | 34 | M | 243 | 9.4 | 4.1 | 2 | Stable | Mild DOE |
| 12 | 45 | M | 389 | 6.5 | 8.0 | 1 | TLL at diagnosis | Symptom free |
| 13 | 42 | M | 392 | 5.2 | 9.5 | 0.5 | TLL at diagnosis | Symptom free |